update - I found some more stuff linked off a pubmed search. I haven't checked the links or investigated the articles so I can't speak to the accuracy of the summaries:
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Researchers injected rats with highly dissolvable fiberglass to assay whether or not byproducts of fiber dissolution were likely carcinogenic. No tumors were generated. They concluded that the degree of carcinogenic potency of a fiber depends primarily on the extent to which it retains its fibrous structure over time, not its chemical composition.
Pulmonary response of mice to fiberglass : cytokinetic and biochemical studies
Comparison of fibrogenic effects of fiberglass and asbestos in rats. Demonstrates that fiberglass requires doses 10x that of asbestos to induce similar levels of fibrosis (scarring) to the lung. Unknown what type/durability of fiberglass was used.
Biopersistence of synthetic vitreous fibers and am...
Biopersistence of synthetic vitreous fibers and am... [Toxicol Appl Pharmacol. 1998] - PubMed result
Comparative look at fiberglass, rockwool and asbestos in hamster inhalation. The very biopersistent fibers like asbestos and specialty high durability ceramics/fiberglass were carcinogenic, while the more rapidly clearing fibers, like normal commercial fiberglass equivalent to oc703, were not at all.
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A one year fiberglass vs. asbestos breathing study in hamsters. Animals exposed to typical commercial fiberglass experienced only nonspecific pulmonary inflammation. However, exposures to a special, high durability fiberglass and asbestos were associated with lung fibrosis and possible mesotheliomas (lung cancer).
Science of the Health Effects of Fibers - Science of the Health Effects of Fibers
OC's research paper references.
Fiberglass Case Studies
Wiley InterScience :: Session Cookies = Pulmonary fibrosis in a carpenter with long-lasting exposure to fiberglass - Takahashi - 1998 - American Journal of Industrial Medicine - Wiley Online Library
Case study of carpenter who inhaled fiberglass unprotected for 41 years. Fibrosis, cystic lesions, and fiber deposition was noted. The authors conclude that this patient's heavy smoking history and long term exposure to fiberglass have contributed to pulmonary fibrosis. Fibers found had all broken down to short lengths, indicating the lung fluid was effective in breaking them down, but macrophages were not able to digest them. Cigarette smoking has an interactive relationship with fibers like asbestos-the asbestos worker who smokes has a much higher chance of developing lung cancer than does the non-smoker.
Clinical Pulmonary Medicine - Abstract: Volume 14(5) September 2007 p 296-301 Respiratory Disease and Fiberglass Exposure: Report of a Case and Review of the Literature. Respiratory Disease and Fiberglass Exposure: Report of a Cas... : Clinical Pulmonary Medicine
Describes a 23 year old with an unusual adverse reaction to fiberglass. It is noted that rare cases of pulmonary fibrosis, acute eosinophilic pneumonia, and sarcoidosis-like pulmonary disease have been described after exposure to fiberglass.
Elsevier Article Locator - Elsevier
Studying 50 cases of sarcoidosis, an immune system disorder, 28% of patients recalled exposure to fiberglass/rockwool. Findings suggest that in susceptible people, mineral deposition from MMVF exposure may contribute to immune issues.
OCCUPATIONAL FIBERGLASS/ROCKWOOL STUDIES
ATSDR - Toxicological Profile: Synthetic Vitreous Fibers - ATSDR - Redirect - Toxicological Profile: Synthetic Vitreous Fibers
The full version of the 2004 US Government review on synthetic vitreous fibers aka manmade vitreous fibers (MMVFs), the group to which rockwool and fiberglass belong. It summarizes all available knowledge on how the body react to these fibers and any associated risks in relatively layman friendly terms.
One subsection of the above containing a referenced overview of all animal studies to date.
A good review article of epidemiological studies following MMVF workers long term. No ill effects have been noted except minor fibrosis among ceramic fiber works. Ceramic fibers are a specialty product that is far more durable and dangerous than any form of fiberglass/rockwool. Neither rockwool nor fiberglass workers were noted to develop the same effect.
Historical cohort study of U.S. man-made vitreous ...[J Occup Environ Med. 2004] - PubMed Result - Historical cohort study of U.S. man-made vitreous ... [J Occup Environ Med. 2004] - PubMed result
Cohort sudy of 4008 women who were MMVF factory workers between 1945 and 1978. No elevated mortality or lung cancer has been observed.
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