I've been lax lately (darn camper), but I usually shoot 2-300 rounds a month. I wouldn't have a chance in hell of an eye shot, and in a situation like that, head shots aren't even recommended.
I know this forum doesn't like this stuff, so I'll just say that anybody that is considering doing ANYTHING for self-defense MUST confer with state and local laws and be sure you're legal in doing whatever it is you do.
As an example, I believe in Illinois you have a "duty to retreat", which means you're supposed to run away and let them carry on, instead of taking action. I'm no lawyer though, so get some valid local advice.
I know the laws well in the states I travel to, but that's it.