Yes the gas regulator will work, this regulator has a smaller gas flow fixed orifice than the ones at a trailer supply, the total amount of gas flow is smaller than the RV type, two appliances like a two burner stove or gas light
with it or a furnace
is about all it can handle.
The inner connective surface is designed to depress the inner working parts of the newer tanks, it is not compatible with other tanks being a different thread.
I have used these in emergency situations with good results as long as the total gas requirements are small with the correct tank.
The other irritating issue is they may not seat properly and simulate a gas restrictions more than the rv type. Also the O rings on the valve need replacing more often.
There have been cold weather issues too in 0 degree climates with these.
I prefer two stage regulators myself for more even regulation across a broader range of total gas flow conditions. eBay saves allot over the stores that gouge.
To answer the question though to your specific question here...Yes...They can within their design specs for an average barbecue.
Happy Camping, Safe Trails.