Ditto on the vibration etc. Just because you don't feel it directly like a vechicle wheel doesn't mean it's a good thihg to allow on the trailer.
Also, I took two Carlisle tires
for my m/c trailer in to be balanced and one was too out of round to be balanced
I got a replacement and it was only marginally better. That was the end of Carlisle tires for me.
I hate to think what might have happened on the highway if I hadn't gone to get them ballanced.